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Synthetic cannabinoids, also known commonly by the name of “Spice” or “K2”, first became available in the U.S. in the mid-2000s. There is no actual marijuana plant in synthetic cannabinoids; however, the action of the chemicals still takes effect on the cannabinoid (THC) receptors in the brain.
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Three patients had full resolution of agitation and one patient had partial resolution of symptoms after receiving sedatives. Four patients received ondansetron for nausea. Three patients received at least 1 l of normal saline.